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AHR antibody

Anti-AHR antibody used in IHC (Paraffin sections) (IHC-P). GTX22100
Anti-AHR antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX22100

Cat. No. GTX22100

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

ICC/IF, IHC-P, ChIP assay, Gel supershift assays

Reactivity

Human, Mouse, Rat
Package
1 ml ($429)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 5 - 20 μg/ml
IHC-P 20 μg/ml
ChIP assay Assay dependent
Gel supershift assays Assay dependent
Not tested in other applications.

Calculated MW

95 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Serum

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Mouse

Immunogen

N-terminal sequence of Aryl hydrocarbon Receptor purified from C57BL/6J mice. [UniProt# P30561]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

aryl-hydrocarbon receptor , Ah , Ahh , Ahre , In , bHLHe76

Cellular Localization

Cytoplasm,Nucleus

Background

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Database

Research Area

DATA IMAGES

Anti-AHR antibody used in IHC (Paraffin sections) (IHC-P). GTX22100

GTX22100 IHC-P Image

IHC-P analysis of human liver tissue using GTX22100 AHR antibody.
Dilution : 20 μg/mL
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)

Anti-AHR antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX22100

GTX22100 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX22100 AHR antibody.
Green : primary antibody
Red : Actin
Blue : DAPI
Dilution : 1:100
Fixation : 10% formalin
Permibilization : 0.5% Triton-X100

REFERENCE

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REVIEW

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Package List Price ($)
$ 429